Otrivin must be administered into the nasal cavities where it exerts as a vasoconstrictive effect leading to decongestion of the nasal and pharyngeal mucosa. Otrivin thus makes it easier to breathe through the nose when suffering from a cold or a chill .Otrivin contains ingredients which should prevent the drying of the nasal mucous membrane.
The effect of otrivin is felt within a few minutes and lasts for upto 10hours. It is indicated in relief of nasal congestion due to colds b, hay fever or other allergic rhinitis,sinusitis .To aid drainage of
secretions in sinus conditions. In otitis condition ,as an adjuvant to decongest the nasopharyngeal mucosa. To facilitate rhinoscopy.
Composition ; Active ingredient xylometazoline hydrochloride ,Pharmaceutical forms :nasal drops 0.5% and 1% nebuliser 1% solution .Nasal gel ; 1% metered dose nasal spray 0.5% and 1% aqueous solution Excipients conservative (benzalkonium chloride).Aromatic agents in the gel .
One spray puff corresponds to 0.14mg(1% solution )and 0.035mg (0.5% solution)of xylometazoline hydrochloride.
Dosage; As directed by the physician.
Side effects;-short lived irritation(burning or dry sensation of the nasal mucosa)in sensitive patients,headache,insomnia, fatigue,palpitations,allergic reactions with dyspnoea,nausea.